Antifungal activity of dodonaea viscosa jacq extract on pathogenic fungi isolated from super ficial skin infection

Antimicrobial activity of solvent extracts of leaves and shoot of Dodonaea viscosa Jacq have been determined against fungi, Aspergillus niger, Aspergillus flavus, Paecilomyces varioti, Microsporum gypseum, and Trichophyton rubrum causing skin diseases. All crude extracts were found to be effective against tested fungi. However chloroform has strong inhibition activity against fungi as compared to ethanol, methanol, ethylacetate and aqueous extracts. More over in present study some basic elements have been analyzed, Al, Ca, Cu, Fe, Mg, Mn, P, S and Zn from the medicinal plant Dodonaea viscosa Jacq. by using atomic absorption spectrophotometry and UV spectrophotometry. The medicinal plant Dodonaea viscosa Jacq contains considerable amount of elements which have therapeutic effects in skin diseases

Isolation of essential elements and inhibition activity of medicinal plant Datura alba Nees against human pathogenic fungi

In this study five extracts such as ethanol, methanol, ethylacetate, chloroform and aqueous extract were obtained from the medicinal plant Datura alba Nees. These extracts were tested against the human pathogenic fungi, Aspergillus niger, Aspergillus flavus, Paecilomyces varioti, Microsporum gypseum, and Trichophyton rubrum. All crude extracts were found to be effective against test organism. Ethanol, methanol, and ethylacetate extracts appeared to be the most effective antifungal agents as compared to the chloroform and aqueous extract. Moreover in present study nine elements, Al, Ca, Cu, Fe, Mg, Mn, P, S and Zn have been determined from the medicinal plant Datura alba Nees, by using atomic absorption spectrophotometry and U.V. spectrophotometry. The medicinal plant Datura alba Nees contains considerable amount of elements which have therapeutic effects in skin diseases

Medicinal utilization of naturally occurring rocks and minerals

The importance of pharmaceutical minerals and rocks have been highlighted. The use of rocks and minerals to produce finished pharmaceutical products find their way for curative and promotive health. A detailed listing of the compounds, naturally occurring minerals as well as rocks and their application if delineated herewith

Naturally occurring Ca++ channel blockers

Ion channel are the set of integral membranes proteins that produce and transduce the electrical signals crucial to the maintenance and function of all living cells, therfore these gate and regulate the flow of ions between the cytoplasmic compartment, and the extracellular space and between subcellular compartment. Ion channels open and close in response to changes in membrance potential and ion concentration. The activity of ion channel is modulated directly through interaction with drugs. It was notied in 1964, that effects of phenylamine and verapamil on cardiac muscles were indistinguishable from the effect of Ca++ withdrawal. Therefore those drugs that inhibited the excitation-contraction couplings are termed as calcium antagonists to indicate that these counteract the effect of Ca++ on the contractile system. Therefore primary objectives of these drugs is inhbition of inward movement of Ca++ through voltage dependent Ca++ channels located in cell membrance. This effect is termed as calcium channel blockers. During the past few years, we have been searching for new calcium-channel blockers from herbal soruce. The reason behind this approach is simple: If cellular calcium regulation is so important in living forms, celluar calcium modulators must be present in plants. Such compounds, if effective as therapeutic agents, would have minimum side effects. Any herb with serous side effects would not have persisted through the years of clinical trials. Plants, therefore, may be potential source of new compounds as calcium channel blockers